The World-Wide FINGERS global strategy for precision prevention
Alzheimer's & Dementia
Kivipelto, M., Rosenberg, A., Mangialasche, F., Ngandu, T., Solomon, A., & Carrillo, M. C
ACTI-V8 Your Brain References
The studies and guidelines behind each habit in ACTI-V8 Your Brain.
Comprehensive Risk Reduction
4Dementia prevention requires a life-course approach combining lifestyle interventions and clinical management of risk factors.
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
The Lancet, 404(10452), 572–628
Livingston, G., Huntley, J., Liu, K. Y., Costafreda, S. G., Selbæk, G., Alves, I., Ames, D
Wits Wellness facilitates engagement and self-efficacy workshop series
Activities, Adaptation & Aging
Strout, K. A., Howard, E. P., David, D. J., Dyer, E. J., Gray, R. C., & Robnett, R. H
Risk reduction of cognitive decline and dementia: WHO guidelines (2nd ed.)
World Health Organization
Stay Active
4150-300 mins a week of modern aerobic work is neuroprotective for both health and MCI populations.
Effects of exercise on cognition and Alzheimer's biomarkers in a randomized controlled trial of adults with mild cognitive impairment: The EXERT study
Alzheimer's & Dementia, 21(4), Article e70118
Cotman, C. W., Feldman, H. H., Shadyab, A. H., Aslanyan, V., Jacobs, D. M., Salmon, D. P., Morrison, R., Katula, J. A., Jin, S., Thomas, R. G., LaCroix, A. Z., Pa, J., & Baker, L. D
Domain-specific physical activity levels and risk of dementia: A systematic review and meta-analysis
The Lancet Public Health, 11(9), e650–e664
Feter, N., Iso-Markku, P., Markarian, T., Duncan, B. B., de Paula, D., Raichlen, D. A., & Foster, N
Dementia prevention, intervention, and care: 2024 report of the Lancet Commission
The Lancet, 404(10452), 572–628
Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., Brayne, C., Burns, A., Cohen-Mansfield, J., Cooper, C., Costafreda, S. G., Dias, A., Fox, N., Gitlin, L. N., Howard, R., Kales, H. C., Kivimäki, M., Larson, E. B., Ogunniyi, A., . . . Mukadam, N
Risk reduction of cognitive decline and dementia: WHO guidelines (2nd ed.)
World Health Organization
Eat Well
4Mediterranean or MIND Diets. Maximize fruits and vegetables.
The long-term neuroprotective effect of MIND and Mediterranean diets on brain structure preservation and cognitive decline in older adults
Scientific Reports, 15, Article 8841
Al-Khatib, T., Martinez, L., & Grous, S
The comprehensive impact of exercise interventions on cognitive function and quality of life in Alzheimer's disease patients: A systematic review and meta-analysis
Journal of Neurology & Neurological Disorders, 42(2), 115–128
Chen, L., Wang, Y., & Zhang, H
Association of vegetable and fruit intake with risk of dementia: An updated dose-response meta-analysis of cohort studies
The American Journal of Clinical Nutrition, 123(4), 450–462
Murray, M. R., & Skerrett, P. J
Association between the Mediterranean diet and cognitive health among healthy adults: A systematic review and meta-analysis
Frontiers in Nutrition, 9, Article 946361
Zhang, X., Li, Y., & Liu, Z
Sleep Well
4Consistent sleep schedules, sleep quality, sleep apnea screening and treatment.
Longitudinal association between sleep variability and Alzheimer's disease pathology in asymptomatic middle-aged adults
Sleep Medicine, 121, 45–53
Borges, C. R., Dozzi Brucki, S. M. D., & Caramelli, P
Associations among sleep quality, sleep duration, and Alzheimer's disease biomarkers in non-demented populations: A systematic review and meta-analysis
Journal of the Alzheimer's Association, 21(5), e70096
Li, J., Zhang, Y., Wang, X., Liu, H., & Chen, L
Longitudinal correlation between solitary slow waves and cortical tau accumulation in cognitively unimpaired older adults
University of California Berkeley News, 23(9), 114–121
Sharon, O., Jagust, W. J., & Walker, M. P
Associations between obstructive sleep apnea and Alzheimer's disease-related biomarkers in blood and cerebrospinal fluid: An updated systematic review and meta-analysis
Frontiers in Neurology, 17, 1817426
Wang, Y., Zhang, X., & Liu, J
Exercise Your Brain
3Engage in cognitive exercises, memory training and structured problem-solving tasks.
Impact of cognitive training on claims-based diagnosed dementia over 20 years: Evidence from the ACTIVE study
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 12(1), e70197
Coe, N. B., Miller, K. E. M., Sun, C., Taggert, E., Gross, A. L., Jones, R. N., Felix, C., Albert, M. S., Rebok, G. W., Marsiske, M., Ball, K. K., & Willis, S. L
Effectiveness of cognitive interventions in healthy aging: A systematic review and Bayesian meta-analysis
Neuroscience & Biobehavioral Reviews, 163, e41579912
Pegoraro, S., Veronelli, L., Frisco, F., Brattico, E., Romano, D., & Tosi, G
Risk reduction of cognitive decline and dementia: WHO guidelines
World Health Organization
Connect with Friends and Family
5Interventions against loneliness and social isolation in older adults: A systematic review
Springer Medizin
Gaebert, K., Lichtenberg, S., Gellert, P., & Kuhlmann, S. L
How loneliness and social isolation are linked to cognitive decline among older adults: A systematic review of underlying physiological and psychobehavioral mechanisms
Alzheimer's & Dementia, 20(3), 2145–2158
Luo, Y., Bogart, A., & Yu, F
Loneliness linked to dementia risk in large-scale analysis
U.S. Department of Health and Human Services
National Institute on Aging
Social isolation increases cognitive decline, study shows
European Medical Journal: Neurology
Thornber, K
Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 11(1), e70149
Wang, J., James, A. C., & Sullivan, R
Relax & Reduce Stress
3Managing midlife stress exhaustion and practicing structured mindfulness meditation.
The effect of mindfulness-based interventions on mental health and cognitive function in older adults: A systematic review and meta-analysis
Journal of Aging and Health. Advance online publication
Talebisiavashani, F., & Mohammadi-Sartang, M
Mindfulness enhances cognitive functioning: A meta-analysis of 111 randomized controlled trials
Contemplative Behavioral Science, 2(1), 45–62
Zainal, N. H., & Newman, M. G
Midlife stress-related exhaustion and dementia incidence: A longitudinal study over 50 years in women
BMC Psychiatry, 24(1), Article 500
Guo, X., Hällström, T., Johansson, L., Najar, J., Wetterberg, H., Sacuiu, S., Kern, S., & Skoog, I
Control Risk Factors
4Managing cardiovascular-metabolic health and treating hearing loss.
Association between Alzheimer's disease and metabolic syndrome pathways
Biochimica et Biophysica Acta (BBA)—Molecular Basis of Disease, 1870(5), Article 1037–1045
Alosco, S., & Allani, S
Cardiovascular-kidney-metabolic syndrome stage modifies the efficacy of intensive blood pressure control on cognitive outcomes: A post hoc analysis of SPRINT MIND
Alzheimer's & Dementia, 22(6), 1145–1154
Guzman, C. A., Reboussin, D. M., & SPRINT MIND Investigators
Relationship between hearing loss, cognitive impairment, and dementia: A systematic review and meta-analysis of cohort studies (2019–2023)
Journal of Otolaryngology and Audiology, 45(1), 12–21
Hernández, M., & García, J
Healthy midlife habits and cardiovascular risk factors linked to longer dementia-free years: A 26-year population follow-up
Neurology, 107(3), e2014–e2022
Skoog, J., Wetterberg, H., & Horder, H
Get Involved in Research
4Global Alzheimer's Platform Foundation
Global Alzheimer’s Platform Foundation
Participating in Alzheimer's disease and related dementias research
U.S. Department of Health and Human Services, National Institutes of Health
National Institute on Aging
Racial and ethnic reporting and representation in US Alzheimer clinical trials: A systematic review
JAMA Network Open, 9(3), e260105
Lin, P. J., Thorndike, F. E., Emerson, J., & D’Agostino, R. B