Now Available

Used to support FDA clearance
for the first blood-based biomarker test for Alzheimer’s disease.

Highly characterized biospecimens for breakthrough research.

GAP's Biospecimen Discovery Portal Request more information

SPECIMEN ID

BH-001
P-0048-A12

Standards ICH GCP · IRB Approved

Storage −80°C continuous

Cohorts CN · MCI · Mild AD

Sample Plasma · Whole Blood · CSF

Inventory 100,000+ aliquots ready to ship

Bio-HermesApheleia

Protocol-driven & IRB Approved

GCP-compliant

Demographically diverse

Robust blood biomarker data

Aβ (beta) PET datasets

A Foundation-Built Biorepository

Intentionally designed to reflect the real-world diversity of people with Alzheimer’s.

The Global Alzheimer’s Platform Foundation® (GAP) has successfully compiled a biospecimen database with comprehensive participant representation across cognition, ethnicity, and race — ensuring your research is for everyone.

These were collected from volunteers in three GAP-sponsored studies: Bio-Hermes-001, Bio-Hermes-002, and Apheleia-001. This unique repository of biological specimens offers an unprecedented opportunity to advance Alzheimer’s disease research, and can be made available to you through our online portal.

The Standard in AD Biorepositories

Most comprehensive, clinically validated biorepository.

Comprehensive & High Quality Biospecimens

Standardized handling · Continuous −80°C SDTM formatted data

Standards and Access

Bio-Hermes-001, Bio-Hermes-002, and Apheleia-001 biospecimens adhere to ICH GCP standards and have IRB-approved protocols. Access to samples is supported through a streamlined process designed to simplify use in qualified research settings.

Collection and Storage

Each biospecimen is collected and processed according to strict protocols defined in our comprehensive lab manual. These procedures are designed to prevent freeze-thaw cycles and ensure continuous storage at −80°C.

Clinical and Industry Use

Bio-Hermes-001 biospecimens have supported FDA clearance for the first blood-based biomarker test, as well as validation across leading diagnostic companies.

Data Included

Available aliquots include rich clinical data, demographics, blood- and digital biomarkers, speech analytics, oculomotor assessments, genomics, proteomics, Aβ and Tau PET results, and MRI scans.

Used to support FDA clearance for the first blood-based biomarker test for Alzheimer’s disease.

Read the announcement

In-Practice & Best Usages

Diagnostics

Early-stage development can be accelerated by using the same biospecimens that have established readouts from peer-based testing. Teams can also interrogate performance in the intermediate zone and concentrate on a specific sample type. Additionally, GAP can organize defined sample cohorts — such as cognitive impairment status, USP status, and/or Amyloid/Tau PET status — for use in low limit detection assays. GAP provides the tools to plot and review receiver operating characteristic (ROC) curves.

Early Researchers

Often, researchers and scientists are seeking biospecimens to complete their cohort. These are typically clinically annotated but have limited biomarker data. GAP can offer biospecimens to support these efforts, especially when PET/CT data isn’t available. Depending on your research focus, GAP can also curate specific cohorts tailored to your biomarker requirements.

Multidimensional, Deeply Annotated Datasets

GAP’s biospecimen repository…

Every aliquot is paired with the clinical and imaging context researchers need.

CN · MCI · Mild AD

Most extensively characterized biospecimens of cognitively normal, MCI, and Mild AD cohorts in Alzheimer's disease to date.

Over 100,000+ aliquots ready to ship.

Plasma + Whole Blood + CSF

Highly annotated whole blood and plasma samples — clinically collected and consistently processed.

Bulk Pricing

Bulk pricing and incentives considered for larger orders. Talk to the Business Development team.

Frequently Asked

Questions.

Bio-Hermes-001 and Apheleia-001 sample sets are complete, as those studies have ended. Bio-Hermes-002 biospecimens are added to the repository as that study progresses. The inventory listing is updated as biospecimens are reserved/shipped.

GAP can provide inventory upon request based on your needs. Once your request has been approved and payment has been received, the biospecimens are reserved and then promptly shipped.

GAP is interested in improving the research environment. Pricing incentives can be considered for larger orders.

Contact

Tell us about your sample needs.

Business Development Team

We'll find the right cohort for your research.

Tell us your sample type, cohort, and target quantities and the Business Development team will be in touch.

Email [email protected]